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Research Studies is a compilation of published research articles funded by ´óÏóAPPor authored by ´óÏóAPPresearchers.

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1 to 5 of 5 Research Studies Displayed
Shaukat A, Wolf J, Rudser K
Multilevel interventions to improve colorectal cancer screening in an urban Native American community: a pilot randomized clinical trial.
This research letter described a randomized controlled trial of an outreach program for completion of colorectal cancer (CRC) screenings at an urban clinic serving the Native American community. The researchers also conducted interviews with patients and providers to understand barriers and facilitators to the organized program and to CRC screening in general.
AHRQ-funded; HS029429.
Citation: Shaukat A, Wolf J, Rudser K . Multilevel interventions to improve colorectal cancer screening in an urban Native American community: a pilot randomized clinical trial. Clin Gastroenterol Hepatol 2024 Aug; 22(8):1744-46.e1. doi: 10.1016/j.cgh.2024.01.044..
Keywords: Cancer: Colorectal Cancer, Cancer, Racial and Ethnic Minorities, Screening, Urban Health, Rural Health, Rural Health
Gautom P, Rosales AG, Petrik AF
Evaluating the reach of a patient navigation program for follow-up colonoscopy in a large Federally Qualified Health Center.
This article described PRECISE, a randomized study of comparing patient navigation (PN) with usual care conducted as a partnership between two large health systems in the Pacific Northwest. The researchers reported the number of contact attempts needed to successfully reach navigated patients and used logistic regression to report demographic and healthcare utilization characteristics associated with patients allocated to PN who were successfully reached. Of the 479 patients allocated to the PN intervention, 382 were reached within 18 call attempts, and nearly all patients were reached within six contact attempts. The researcher concluded that their findings could guide future efforts to optimize the reach of PN programs.
AHRQ-funded; HS026370.
Citation: Gautom P, Rosales AG, Petrik AF . Evaluating the reach of a patient navigation program for follow-up colonoscopy in a large Federally Qualified Health Center. Cancer Prev Res 2024 Jul 2; 17(7):325-33. doi: 10.1158/1940-6207.Capr-23-0498..
Keywords: Colonoscopy, Screening, Cancer: Colorectal Cancer, Prevention, Cancer
Rivera Rivera JN, AuBuchon KE, Schubel LC
Supporting ColoREctal Equitable Navigation (SCREEN): a protocol for a stepped-wedge cluster randomized trial for patient navigation in primary care.
This study addresses the higher incidence and mortality rates of colorectal cancer (CRC) among Black and Hispanic/Latino populations in the United States. The researchers are conducting a stepped-wedge cluster randomized trial to implement and scale a patient navigation program aimed at improving CRC screening rates in these communities. The trial involves 15 primary care clinics, with a phased introduction of the intervention over six steps, each lasting six months. Following an initial six-month baseline data collection period, clinics are randomized to join the intervention arm in groups of three every six months until all clinics have transitioned. The implementation process includes clinic training and education, electronic health record infrastructure changes, stakeholder relationship building, readiness assessment, and ongoing feedback. Guided by the Practical, Robust Implementation Sustainment Model (PRISM), the study focuses on effectiveness, reach, provider adoption, and implementation aspects. The researchers plan to document adaptations to both the patient navigation intervention and implementation strategies. To promote health equity, the study incorporates multilevel stakeholder input through interviews and a community advisory board, influencing various aspects of the project from planning to dissemination. Provider feedback will include updates on disparities in screening orders and completions. The researchers aim to understand how to tailor a patient navigation program for CRC screening across diverse primary care settings with varying baseline screening rates, payor mix, proximity to specialty care, and patient volume.
AHRQ-funded; HS029807.
Citation: Rivera Rivera JN, AuBuchon KE, Schubel LC . Supporting ColoREctal Equitable Navigation (SCREEN): a protocol for a stepped-wedge cluster randomized trial for patient navigation in primary care. Implement Sci Commun 2024 Jun 3; 5(1):60. doi: 10.1186/s43058-024-00598-5.
Keywords: Cancer: Colorectal Cancer, Screening, Primary Care, Disparities, Racial and Ethnic Minorities
Campbell KA, Sternberg SB, Benneyan J
Completion rates and timeliness of diagnostic colonoscopies for rectal bleeding in primary care.
This study looked at the completion rates and timeliness of diagnostic colonoscopies for rectal bleeding in primary care, as rectal bleeding is usually the most common presenting symptom of colorectal cancer. This retrospective cohort study was a medical record review of patients aged ≥ 40 with index diagnosis of rectal bleeding at 2 primary practices-an urban academic practice and affiliated community health center-between January 1, 2018, and December 31, 2020. Primary outcomes were percentages of patient cases classified as having completed recommended follow-up workup ("closed loop") vs. not ("open loop"). A total of 837 patients had been coded with rectal bleeding, with 67 excluded leaving 770 patients included. A total of 172 patients (22.3%) failed to undergo timely recommended workup. Reasons for a failed timely workup included the majority not having a procedure ordered, or the procedure was ordered but never scheduled or cancelled and not kept.
AHRQ-funded; HS027282.
Citation: Campbell KA, Sternberg SB, Benneyan J . Completion rates and timeliness of diagnostic colonoscopies for rectal bleeding in primary care. J Gen Intern Med 2024 May; 39(6):985-91. doi: 10.1007/s11606-023-08513-9..
Keywords: Diagnostic Safety and Quality, Screening, Cancer: Colorectal Cancer, Primary Care, Prevention, Cancer
Liu PH, Singal AG, Murphy CC
Colorectal cancer screening receipt does not differ by 10-year mortality risk among older adults.
This study examined receipt of past-year colorectal cancer (CRC screening) according to predicted 10-year mortality risk among 25,888 community-dwelling adults aged 65-84 years who were not up-to-date with screening in the nationwide National Health Interview Survey. Ten-year mortality risk was estimated using a validated index with the lowest to highest quintiles of the index ranging from 12%-79%. The authors also examined the proportion of screening performed among adults with life expectancy <10 years. They found that the prevalence of past-year CRC screening was 39.5%, 40.6%, 38.7%, 36.4%, and 35.4%, from the lowest to highest quintile of 10-year mortality risk, demonstrating that the odds of CRC screening did not differ in the lowest vs highest quintile. One-quarter of past-year CRC screening occurred in adults with life expectancy <10 years, and more than half (50.7%) of adults aged 75-84 years had 10-year mortality risk ≥50% at the time of screening. Invasive but not noninvasive screening increased as 10-year mortality risk increased among adults aged 70-79 years.
AHRQ-funded; HS022418.
Citation: Liu PH, Singal AG, Murphy CC . Colorectal cancer screening receipt does not differ by 10-year mortality risk among older adults. Am J Gastroenterol 2024 Feb; 119(2):353-63. doi: 10.14309/ajg.0000000000002536.
Keywords: Elderly, Cancer: Colorectal Cancer, Mortality, Screening, Colonoscopy

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