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Research Studies is a compilation of published research articles funded by 大象APPor authored by 大象APPresearchers.

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1 to 18 of 18 Research Studies Displayed
Marcotte LM, Wheat CL, Rao M
Evaluating equity in a national virtual care management intervention: delivery and outcomes by race/ethnicity among veterans with hypertension and diabetes.
The objective of this study was to evaluate whether the Preventive Health Inventory (PHI), a virtual care management intervention implemented in the Veterans Health Administration (VHA), was delivered equitably among racial/ethnic groups. Researchers used data from the VHA Corporate Data Warehouse among veterans enrolled in primary care nationally. Their findings suggested that the PHI intervention was deployed equitably across race/ethnicity groups without significantly impacting most existing inequities in hypertension and diabetes.
AHRQ-funded; HS026369.
Citation: Marcotte LM, Wheat CL, Rao M . Evaluating equity in a national virtual care management intervention: delivery and outcomes by race/ethnicity among veterans with hypertension and diabetes. Health Serv Res 2024 Dec; 59(6):e14352. doi: 10.1111/1475-6773.14352.
Keywords: Diabetes, Blood Pressure, Racial and Ethnic Minorities, Disparities, Primary Care, Telehealth, Health Information Technology (HIT)
Engelberg RS, Scheidell JD, Islam N
Associations between incarceration history and risk of hypertension and hyperglycemia: consideration of differences among Black, Hispanic, Asian and White Subgroups.
This study鈥檚 objective was to assess racial/ethnic group differences in the association between incarceration and hypertension and hyperglycemia. The authors performed a secondary data analysis using the National Longitudinal Survey of Adolescent to Adult Health (Add Health). They used Poisson regression to estimate the associations between lifetime history of incarceration reported during early adulthood with hypertension and hyperglycemia outcomes measured in mid-adulthood, including incident diagnosis. They evaluated whether associations varied by self-reported race/ethnicity (non-Hispanic White, non-Hispanic Black, Hispanic, and Asian) with an analytic sample of 4,015 Add Health respondents. Outcome measures included hypertension, systolic blood pressure >130 mmHG, and hyperglycemia. There was no evidence of an association between incarceration and measured health outcomes among non-Hispanic Black and non-Hispanic White participants. Among Hispanic participants, incarceration was associated with hyperglycemia (Adjusted Risk Ratio (ARR): 2.1), but not with hypertension risk. Incarceration was associated with elevated systolic blood pressure (ARR: 3.1) and hypertension (ARR: 1.7) among Asian participants, but not with hyperglycemia risk. Incarceration was associated with incident hypertension (ARR 2.5) among Asian subgroups.
AHRQ-funded; HS026120.
Citation: Engelberg RS, Scheidell JD, Islam N . Associations between incarceration history and risk of hypertension and hyperglycemia: consideration of differences among Black, Hispanic, Asian and White Subgroups. J Gen Intern Med 2024 Jan; 39(1):5-12. doi: 10.1007/s11606-023-08327-9..
Keywords: Vulnerable Populations, Racial and Ethnic Minorities, Blood Pressure, Cardiovascular Conditions, Risk
Gianaris K, Vargas GB, Johnson M
Perceived susceptibility to chronic kidney disease and hypertension self-management among Black and White live kidney donors.
This study examines the theory whether Black kidney donors are more likely than White donors to develop hypertension (HTN) and chronic kidney disease after donation. The authors ascertained electronic medical records and phone survey data from live donors enrolled in the multi-center Wellness and Health Outcomes of LivE Donors (WHOLE-Donor) Hypertension Care Study between May 2013 and April 2020. The study cohort included 318 US-based live kidney donors who developed post-donation HTN with 57.6% female, 78.9% White, 18.6% Black, and a mean age of 46.7 years. Donors with diabetes or who were older than 50 years reported being moderately or strongly concerned about kidney disease. A large majority (87%) reported taking at least one action to help control blood pressure, with no significant differences by sociodemographic factors. They found no substantial differences in perceived susceptibility to kidney disease among Black and White donors, despite published evidence that Black donors may experience greater risk of developing kidney disease than White donors.
AHRQ-funded; HS024600.
Citation: Gianaris K, Vargas GB, Johnson M . Perceived susceptibility to chronic kidney disease and hypertension self-management among Black and White live kidney donors. Ethn Dis 2022 Spring;32(2):101-08. doi: 10.18865/ed.32.2.101..
Keywords: Kidney Disease and Health, Chronic Conditions, Racial and Ethnic Minorities, Transplantation, Patient Self-Management, Blood Pressure
Akwo EA, Robinson-Cohen C, Chung CP
Association of apparent treatment-resistant hypertension with differential risk of end-stage kidney disease across racial groups in the million veteran program.
Apparent treatment-resistant hypertension (ATRH) has been linked to end-stage kidney disease (ESKD) and cardiovascular disease. In this study, the investigators tested the hypothesis that the effect of ATRH on ESKD is greater in Black patients than in White patients and investigated the effect of ATRH on ESKD independent of APOL1 genotype. The investigators concluded that ATRH was associated with an elevated risk of adverse kidney and cardiovascular outcomes. The effect of ATRH on incident ESKD was magnified among patients with reduced kidney function as well as Black patients, independently of APOL1 genotype.
AHRQ-funded; HS026395.
Citation: Akwo EA, Robinson-Cohen C, Chung CP . Association of apparent treatment-resistant hypertension with differential risk of end-stage kidney disease across racial groups in the million veteran program. Hypertension 2021 Aug;78(2):376-86. doi: 10.1161/hypertensionaha.120.16181..
Keywords: Blood Pressure, Kidney Disease and Health, Racial and Ethnic Minorities
Odlum M, Moise N, Kronish IM
Trends in poor health indicators among Black and Hispanic middle-aged and older adults in the United States, 1999-2018.
This study used records extracted from the Behavioral Risk Factor Surveillance System to determine which health indicators have improved or became worse among Black and Hispanic middle-aged (45 and older) adults compared to Whites from 1999 to 2018. This data is required by the Minority Health and Health Disparities Research and Education Act of 2000. A sample included of 4,856,326 participants, of them 60.9% women, mean age 60.4. During the last 20 years, Black adults showed an overall decrease showing improvement in uninsured status and physical inactivity while showing an overall increase in hypertension, diabetes, asthma, and stroke, and also the same increases and decreases in the Black-White gap. Hispanic adults showed improvement in physical inactivity and perceived poor health, while they showed overall deterioration in hypertension and diabetes. The Hispanic-White gap improved in coronary heart disease, stroke, kidney disease, asthma, arthritis, depression and physical inactivity while it increased for diabetes, hypertension, and uninsured status.
AHRQ-funded; HS025198.
Citation: Odlum M, Moise N, Kronish IM . Trends in poor health indicators among Black and Hispanic middle-aged and older adults in the United States, 1999-2018. JAMA Netw Open 2020 Nov 2;3(11):e2025134. doi: 10.1001/jamanetworkopen.2020.25134..
Keywords: Elderly, Racial and Ethnic Minorities, Disparities, Health Status, Health Insurance, Diabetes, Blood Pressure, Chronic Conditions
Cuffee YL, Rosal M, Hargraves JL
Does home remedy use contribute to medication nonadherence among Blacks with hypertension?
The objective of this study was to examine home remedy (HR) use among Blacks with hypertension and to determine if home remedy use is correlated with blood pressure and medication adherence. Data was obtained from the TRUST study conducted 2006-2008. Findings showed that the use of HR and the number of HRs used may be associated with medication nonadherence and with higher systolic and diastolic blood pressure among Blacks with hypertension. Recommendations included that health care providers need to be aware of health behaviors that may serve as barriers to medication adherence, such as the use of home remedies.
AHRQ-funded; HS020755.
Citation: Cuffee YL, Rosal M, Hargraves JL . Does home remedy use contribute to medication nonadherence among Blacks with hypertension? Ethn Dis 2020 Summer;30(3):451-58. doi: 10.18865/ed.30.3.451..
Keywords: Patient Adherence/Compliance, Medication, Blood Pressure, Racial and Ethnic Minorities, Cardiovascular Conditions
Mefford MT, Goyal P, Howard G
The association of hypertension, hypertension duration, and control with incident heart failure in black and white adults.
Associations between hypertension and some cardiovascular diseases are stronger in black vs white adults. In this study, the investigators examined associations of hypertension, hypertension duration, and control with incident heart failure (HF) in black and white REasons for Geographic And Racial Differences in Stroke study participants (n = 25 770) who were followed for incident HF hospitalization (n = 947) from enrollment in 2003-2007 through 2015.
AHRQ-funded; HS013852.
Citation: Mefford MT, Goyal P, Howard G . The association of hypertension, hypertension duration, and control with incident heart failure in black and white adults. J Clin Hypertens 2020 May;22(5):857-66. doi: 10.1111/jch.13856..
Keywords: Blood Pressure, Heart Disease and Health, Cardiovascular Conditions, Racial and Ethnic Minorities
Lor M, Koleck TA, Bakken S
Association between health literacy and medication adherence among Hispanics with hypertension.
This study examined the association between health literacy and medication adherence among Hispanic adults with hypertension. A cross-sectional survey of 1355 Hispanic adults, mostly Dominicans who self-report hypertension was conducted. After controlling for age, sex, birth country, education level, recruitment location, depression, anxiety, and sleep disturbance inadequate health literacy was associated with a lower adherence score.
AHRQ-funded; HS019853; HS022961.
Citation: Lor M, Koleck TA, Bakken S . Association between health literacy and medication adherence among Hispanics with hypertension. J Racial Ethn Health Disparities 2019 Jun;6(3):517-24. doi: 10.1007/s40615-018-00550-z..
Keywords: Blood Pressure, Health Literacy, Patient Adherence/Compliance, Medication, Racial and Ethnic Minorities
Bandi P, Goldmann E, Parikh NS
Age-related differences in antihypertensive medication adherence in Hispanics: a cross-sectional community-based survey in New York City, 2011-2012.
US Hispanics, particularly younger adults in New York City, have a higher prevalence of uncontrolled hypertension than do people of other racial/ethnic groups. This study found that in younger adults, heavy alcohol consumption, a longer duration of hypertension, and recent poor physical health were negatively associated with high adherence. In older adults, advancing age, higher education level, high knowledge of hypertension control, and insurance status were positively associated with high adherence.
AHRQ-funded; HS022961.
Citation: Bandi P, Goldmann E, Parikh NS . Age-related differences in antihypertensive medication adherence in Hispanics: a cross-sectional community-based survey in New York City, 2011-2012. Prev Chronic Dis 2017 Jul 13;14:E57. doi: 10.5888/pcd14.160512.
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Keywords: Blood Pressure, Medication, Patient Adherence/Compliance, Racial and Ethnic Minorities
Tajeu GS, Mennemeyer S, Menachemi N
Cost-effectiveness of antihypertensive medication: exploring race and sex differences using data from the REasons for Geographic and Racial Differences in Stroke Study.
The researchers compared the cost-effectiveness of antihypertensive medication treatment versus no-treatment in white and black adults. They concluded that antihypertensive medication treatment is cost-saving and increases quality-adjusted life-years (QALYs) for all groups considered in the model, particularly among black adults.
AHRQ-funded; HS013852.
Citation: Tajeu GS, Mennemeyer S, Menachemi N . Cost-effectiveness of antihypertensive medication: exploring race and sex differences using data from the REasons for Geographic and Racial Differences in Stroke Study. Med Care 2017 Jun;55(6):552-60. doi: 10.1097/mlr.0000000000000719.
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Keywords: Medication, Blood Pressure, Healthcare Costs, Racial and Ethnic Minorities, Stroke
Diaz KM, Booth JN, 3rd, Seals SR
Physical activity and incident hypertension in African Americans: the Jackson Heart Study.
The purpose of this study was to examine the association of physical activity with incident hypertension among African Americans. It found no statistically significant associations observed for overall physical activity, or work, active living, and household-related physical activities. Results suggest that regular moderate-vigorous physical activity or sport/exercise-related physical activity may reduce the risk of developing hypertension in African Americans.
AHRQ-funded; HS023009.
Citation: Diaz KM, Booth JN, 3rd, Seals SR . Physical activity and incident hypertension in African Americans: the Jackson Heart Study. Hypertension 2017 Mar;69(3):421-27. doi: 10.1161/hypertensionaha.116.08398.
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Keywords: Blood Pressure, Lifestyle Changes, Racial and Ethnic Minorities, Risk
Redmond N, Booth JN, 3rd, Tanner RM
Prevalence of masked hypertension and its association with subclinical cardiovascular disease in African Americans: results from the Jackson Heart Study.
Using data from the Jackson Heart Study, an exclusively African American population-based cohort, the researchers evaluated the association of masked hypertension and prehypertension with left ventricular mass index and common carotid intima media thickness. Masked hypertension was common among African Americans with prehypertension and also normal clinic blood pressure, and was associated with subclinical cardiovascular disease.
AHRQ-funded; HS023009.
Citation: Redmond N, Booth JN, 3rd, Tanner RM . Prevalence of masked hypertension and its association with subclinical cardiovascular disease in African Americans: results from the Jackson Heart Study. J Am Heart Assoc 2016 Mar 29;5(3):e002284. doi: 10.1161/jaha.115.002284.
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Keywords: Blood Pressure, Heart Disease and Health, Cardiovascular Conditions, Racial and Ethnic Minorities
Rivera-Soto WT, Rodriguez-Figueroa L
Is waist-to-height ratio a better obesity risk-factor indicator for Puerto Rican children than is BMI or waist circumference?
This study aimed to explore the association of a single blood pressure reading with 3 different obesity indicators (WC, BMI, and WHtR). Its findings suggest the possibility of higher prevalence of high blood pressure in obese Puerto Rican children. The waist-to height ratio could be the best indicator to measure obesity and potential hypertension in Puerto Rican children.
AHRQ-funded; HS014060.
Citation: Rivera-Soto WT, Rodriguez-Figueroa L . Is waist-to-height ratio a better obesity risk-factor indicator for Puerto Rican children than is BMI or waist circumference? P R Health Sci J 2016 Mar;35(1):20-5.
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Keywords: Racial and Ethnic Minorities, Obesity, Children/Adolescents, Risk, Blood Pressure
Booth JN, 3rd, Redmond N, Sims M
The association of reduced lung function with blood pressure variability in African Americans: data from the Jackson Heart Study.
The reseaerchers evaluated the association between percent predicted lung-function and 24-hour blood pressure variability (BPV) in 1008 African Americans enrolled in the Jackson Heart Study who underwent ambulatory blood pressure (BP) monitoring. They found that lung-function was not associated with increased 24-hour BPV.
AHRQ-funded; HS023009.
Citation: Booth JN, 3rd, Redmond N, Sims M . The association of reduced lung function with blood pressure variability in African Americans: data from the Jackson Heart Study. BMC Cardiovasc Disord 2016 Jan 12;16:6. doi: 10.1186/s12872-015-0182-2.
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Keywords: Cardiovascular Conditions, Blood Pressure, Racial and Ethnic Minorities, Risk, Respiratory Conditions
Bangalore S, Ogedegbe G, Gyamfi J
Outcomes with angiotensin-converting enzyme inhibitors vs other antihypertensive agents in hypertensive blacks.
The study鈥檚 objective was to evaluate the effectiveness of angiotensin-converting enzyme inhibitors when compared with other antihypertensive agents in hypertensive blacks. It found that in a large cohort of hypertensive blacks, angiotensin-converting enzyme inhibitors were associated with less benefit when compared with calcium channel blockers or thiazide diuretics.
AHRQ-funded; HS018589.
Citation: Bangalore S, Ogedegbe G, Gyamfi J . Outcomes with angiotensin-converting enzyme inhibitors vs other antihypertensive agents in hypertensive blacks. Am J Med 2015 Nov;128(11):1195-203. doi: 10.1016/j.amjmed.2015.04.034..
Keywords: Blood Pressure, Racial and Ethnic Minorities, Medication, Outcomes, Cardiovascular Conditions, Patient-Centered Outcomes Research, Evidence-Based Practice, Comparative Effectiveness
Zhao B, Jose PO, Pu J
Racial/ethnic differences in hypertension prevalence, treatment, and control for outpatients in Northern California 2010-2012.
The purpose of this paper is to study the prevalence, treatment, and control of hypertension among rapidly--growing minority groups. The authors found substantial racial/ethnic variation in hypertension prevalence, treatment, and control in the study population in northern California. Filipino and non-Hispanic black women and men are at especially high risk for hypertension and may have more difficulty in achieving adequate blood pressure control.
AHRQ-funded; HS019815.
Citation: Zhao B, Jose PO, Pu J . Racial/ethnic differences in hypertension prevalence, treatment, and control for outpatients in Northern California 2010-2012. Am J Hypertens 2015 May;28(5):631-9. doi: 10.1093/ajh/hpu189.
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Keywords: Blood Pressure, Racial and Ethnic Minorities, Cardiovascular Conditions, Medication, Ambulatory Care and Surgery
Pavlik VN, Chan W, Hyman DJ
Designing and evaluating health systems level hypertension control interventions for African-Americans: lessons from a pooled analysis of three cluster randomized trials.
This study conducted a pooled analysis of three projects that aimed to evaluate clinically feasible interventions to effect changes in medical care delivery leading to an increased proportion of African American patients with controlled blood pressure (BP). The analysis of trial results to determine the magnitude of the combined intervention effect found that pooled BP did not differ significantly between intervention and control clusters.
AHRQ-funded; HS021667.
Citation: Pavlik VN, Chan W, Hyman DJ . Designing and evaluating health systems level hypertension control interventions for African-Americans: lessons from a pooled analysis of three cluster randomized trials. Curr Hypertens Rev 2015;11(2):123-31..
Keywords: Blood Pressure, Racial and Ethnic Minorities, Healthcare Delivery, Prevention, Care Management
Schoenthaler A, Montague E, Baier Manwell L
Patient-physician racial/ethnic concordance and blood pressure control: the role of trust and medication adherence.
The researchers examined the associations between racial/ethnic concordance and blood pressure (BP) control to determine whether patient trust and medication adherence mediate these associations. They found that higher levels of trust were associated with better medication adherence and a tendency toward better BP control, irrespective of patient鈥損hysician racial/ethnic concordance.
AHRQ-funded; HS011955.
Citation: Schoenthaler A, Montague E, Baier Manwell L . Patient-physician racial/ethnic concordance and blood pressure control: the role of trust and medication adherence. Ethn Health 2014;19(5):565-78. doi: 10.1080/13557858.2013.857764..
Keywords: Blood Pressure, Racial and Ethnic Minorities, Medication, Patient Adherence/Compliance

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